Description

(R)-1-[(R)-2-(2''-Diphenylphosphinophenyl)-Ferrocenyl]-Ethyldi-(Bis-3,5-Trifluoromethylphenyl)-Phosphine-(1,5-Cyclooctadiene)-Rhodium(I)]-Tetrafluoroborate is a highly specialized, chiral transition metal complex designed for advanced catalytic applications. This compound matters because it serves as a precise and efficient catalyst for asymmetric synthesis, enabling the production of enantiomerically pure compounds critical in modern chemistry. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and high-value chiral intermediates.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines to produce single-isomer products.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in the development of novel APIs, including cardiovascular, neurological, and oncological drugs.
• Fine Chemical Production: Used in the synthesis of specialty agrochemicals, flavors, fragrances, and advanced materials requiring high enantiomeric purity.
• Academic & Process Chemistry Research: A valuable tool for methodology development and studying structure-activity relationships in homogeneous catalysis.
• Catalyst Ligand Precursor: The sophisticated ferrocenyl phosphine ligand framework can be utilized to develop other custom catalytic systems.

Basic Information

Item	Details
Product Name	(R)-1-[(R)-2-(2''-Diphenylphosphinophenyl)-Ferrocenyl]-Ethyldi-(Bis-3,5-Trifluoromethylphenyl)-Phosphine-(1,5-Cyclooctadiene)-Rhodium(I)]-Tetrafluoroborate
CAS No.	673458-88-3
Molecular Formula	C61H48BF4FeP2Rh
Molecular Weight	1084.57 g/mol
Synonyms	Josiphos SL-J009-1 Rhodium(I) Tetrafluoroborate; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-bis(trifluoromethyl)phenyl)phosphine(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; Rhodium(I)-(R)-(S)-Josiphos(COD) tetrafluoroborate; (R)-(S)-Josiphos-Rh(COD)BF4; Asymmetric Hydrogenation Catalyst J009-1; [Rh((R)-(S)-Josiphos)(COD)]BF4; Chiral Rhodium Ferrocenylphosphine Complex
EINECS	Contact for details

Quality Control

Every batch of our chiral catalyst is produced and tested under strict quality control protocols to ensure exceptional purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as Rhodium content, enantiomeric purity of the ligand, and solvent residues. Our quality system is designed to meet the stringent requirements of process research and cGMP manufacturing environments. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Rhodium Content	9.4 - 9.8 %
Moisture Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.