Description

1H-Indene-1-Methanol,Octahydro-2-Hydroxy-1-Methyl-3-Methylene-,(1R,2S,3Ar,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, functionalized indane core structure makes it a valuable chiral building block for constructing pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs to explore structure-activity relationships (SAR).
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric transformations due to its defined stereocenters, enabling the construction of complex, enantiomerically pure molecules.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of agrochemicals, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis and catalysis.

Basic Information

Item	Details
Product Name	1H-Indene-1-Methanol,Octahydro-2-Hydroxy-1-Methyl-3-Methylene-,(1R,2S,3Ar,7Ar)-Rel-(9Ci)
CAS No.	672936-73-1
Molecular Formula	C12H20O2
Molecular Weight	196.29 g/mol
Synonyms	(1R,2S,3aR,7aR)-Octahydro-2-hydroxy-1-methyl-3-methylene-1H-indene-1-methanol; Rel-(1R,2S,3aR,7aR)-Octahydro-2-hydroxy-1-methyl-3-methylene-1H-indene-1-methanol; (1R,2S,3aR,7aR)-1-(Hydroxymethyl)-2-hydroxy-1-methyl-3-methylidene-2,3,3a,4,5,6,7,7a-octahydro-1H-indene; 1H-Indene-1-methanol, octahydro-2-hydroxy-1-methyl-3-methylene-, (1R,2S,3aR,7aR)-rel-; Chiral Indane Diol Derivative
EINECS	Contact for details

Quality Control

Our 1H-Indene-1-Methanol,Octahydro-2-Hydroxy-1-Methyl-3-Methylene-,(1R,2S,3Ar,7Ar)-Rel-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.