Description

1,4-Dioxaspiro[4.5]Decane-6-Methanol,6,7-Dimethyl-,(6R,7R)-Rel-(9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. Its defined stereochemistry and functionalized spirocyclic structure make it a critical synthon for the development of complex, biologically active molecules. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for synthesizing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block for constructing molecules with specific stereocenters in medicinal chemistry and process development.
• Fine Chemical Production: Serves as a starting material or intermediate for manufacturing specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Catalyst & Ligand Synthesis: Potential use in the development of novel chiral catalysts and ligands for enantioselective transformations.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decane-6-Methanol,6,7-Dimethyl-,(6R,7R)-Rel-(9Ci)
CAS No.	672927-66-1
Molecular Formula	C11H20O3
Molecular Weight	200.27 g/mol
Synonyms	(6R,7R)-6,7-Dimethyl-1,4-dioxaspiro[4.5]decane-6-methanol; rel-(6R,7R)-6,7-Dimethyl-1,4-dioxaspiro[4.5]decane-6-methanol; (6R,7R)-6,7-Dimethyl-1,4-dioxaspiro[4.5]decan-6-ylmethanol; 6,7-Dimethyl-1,4-dioxaspiro[4.5]decane-6-methanol, (6R,7R)-rel-; Chiral Spiroketal Alcohol; Dimethyl Dioxaspirodecane Methanol
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.5]Decane-6-Methanol,6,7-Dimethyl-,(6R,7R)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or GC), chiral purity, and impurity profiles. We operate under a cGMP-compliant mindset, and our quality systems are designed to meet the rigorous standards of the pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.