Description

4,7-Methano-1H-Indene-3-Methanol,3A,4,7,7A-Tetrahydro-1-Hydroxy--α--Methyl-,(-α-R,1R,3As,4R,7S,7Ar)-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex molecules, offering precise structural control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Catalyst & Ligand Development: Serves as a foundational structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for producing specialized polymers with unique thermal or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in complex natural product synthesis and stereochemistry.

Basic Information

Item	Detail
Product Name	4,7-Methano-1H-Indene-3-Methanol,3A,4,7,7A-Tetrahydro-1-Hydroxy--α--Methyl-,(-α-R,1R,3As,4R,7S,7Ar)-(9Ci)
CAS No.	672337-30-3
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(1R,3aS,4R,7S,7aR)-1-Hydroxy-α-methyl-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene-3-methanol; (-)-α-Methyl-1-hydroxy-3a,4,7,7a-tetrahydro-4,7-methanoindene-3-methanol; Chiral indene methanol derivative; Bicyclo[2.2.1]heptane indene methanol; 672337-30-3; (1R,3aS,4R,7S,7aR)-1-Hydroxy-α-methyl-1,3,3a,4,7,7a-hexahydro-4,7-methanoinden-3-ylmethanol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chiral purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We commit to cGMP-compliant practices where required, ensuring suitability for use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.