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4,7-Methano-1H-Indene-3-Methanol,3A,4,7,7A-Tetrahydro-1-Hydroxy--α--Methyl-,(-α-R,1S,3Ar,4S,7R,7As)-Rel-(9Ci) CAS NO 672337-17-6


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CAS No.:672337-17-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4,7-Methano-1H-Indene-3-Methanol,3A,4,7,7A-Tetrahydro-1-Hydroxy--α--Methyl-,(-α-R,1S,3Ar,4S,7R,7As)-Rel-(9Ci) is a complex, stereochemically defined bicyclic organic compound that serves as a high-value chiral building block in advanced chemical synthesis. Its unique, rigid molecular framework and specific stereochemistry make it an essential intermediate for constructing molecules with precise three-dimensional architectures. This compound is primarily sought after by pharmaceutical research and fine chemical organizations for the development of novel active ingredients and specialty materials.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
  • Asymmetric Synthesis: Utilized as a precursor or auxiliary in catalytic asymmetric reactions to induce high enantioselectivity.
  • Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts used in industrial chemical processes.
  • Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or mechanical properties.
  • Agrochemical Synthesis: Potential intermediate in the development of advanced, stereospecific pesticides or herbicides.
  • Academic & Industrial R&D: Used in chemical research to study structure-activity relationships and novel reaction pathways.

Basic Information

Item Details
Product Name 4,7-Methano-1H-Indene-3-Methanol,3A,4,7,7A-Tetrahydro-1-Hydroxy--α--Methyl-,(-α-R,1S,3Ar,4S,7R,7As)-Rel-(9Ci)
CAS No. 672337-17-6
Molecular Formula C12H18O2
Molecular Weight 194.27 g/mol
Synonyms (1S,3aR,4S,7R,7aS)-1-Hydroxy-α-methyl-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene-3-methanol; Rel-(1S,3aR,4S,7R,7aS)-1-Hydroxy-α-methyl-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene-3-methanol; Bicyclic Chiral Alcohol Derivative; Chiral Methanoindene Methanol; (9CI) Identifier Compound; Stereoisomer of Methanoindene Methanol
EINECS Contact for details

Quality Control

We supply this high-purity chiral intermediate under a stringent quality management system. Each batch is characterized and tested to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing chiral purity (enantiomeric excess), assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% e.e.
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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