Description

2H-Pyrano[4,3-B]Pyridine-3-Carbonitrile,7-Ethyl-1,5,7,8-Tetrahydro-7-Methyl-2-Oxo-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial compounds.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2H-Pyrano[4,3-B]Pyridine-3-Carbonitrile,7-Ethyl-1,5,7,8-Tetrahydro-7-Methyl-2-Oxo-(9Ci)
CAS No.	671758-37-5
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25 g/mol
Synonyms	7-Ethyl-1,5,7,8-tetrahydro-7-methyl-2-oxo-2H-pyrano[4,3-b]pyridine-3-carbonitrile; 2H-Pyrano[4,3-b]pyridine-3-carbonitrile, 7-ethyl-1,5,7,8-tetrahydro-7-methyl-2-oxo-; 671758-37-5; 7-Ethyl-7-methyl-2-oxo-1,5,7,8-tetrahydro-2H-pyrano[4,3-b]pyridine-3-carbonitrile; Pyrano[4,3-b]pyridine-3-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 2H-Pyrano[4,3-B]Pyridine-3-Carbonitrile,7-Ethyl-1,5,7,8-Tetrahydro-7-Methyl-2-Oxo-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.