Description

2-[(4,8-Dimethylquinazolin-2-Yl)Amino]-6-{[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Sulfanyl]Methyl}Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its complex heterocyclic structure, which serves as a critical building block in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Process Chemistry Development: Serves as a standard or starting material for scaling up API synthesis under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Employed in university and institutional labs for exploratory chemical biology and drug discovery projects.
• Reference Standard: Can be used as an analytical standard for method development and quality control of related compounds.

Basic Information

Item	Details
Product Name	2-[(4,8-Dimethylquinazolin-2-Yl)Amino]-6-{[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Sulfanyl]Methyl}Pyrimidin-4(3H)-One
CAS No.	669749-20-6
Molecular Formula	C₁₉H₁₈N₈OS₂
Molecular Weight	438.52 g/mol
Synonyms	6-[[(5-Methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-2-[(4,8-dimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone; 2-[(4,8-Dimethylquinazolin-2-yl)amino]-6-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}pyrimidin-4(3H)-one; CAS 669749-20-6; Quinazoline-pyrimidinone-thiadiazole derivative; Advanced heterocyclic building block
EINECS	Contact for details

Quality Control

Our 2-[(4,8-Dimethylquinazolin-2-Yl)Amino]-6-{[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Sulfanyl]Methyl}Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.