Description

3-Biphenyl-3'-Fluoro-Acetic Acid is a high-purity fluorinated biphenyl acetic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a biphenyl core with a fluorine substituent and a reactive carboxylic acid group, enabling precise modifications for target molecule development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for targets requiring fluorinated biphenyl motifs to enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a versatile building block for creating fluorinated biphenyl-based mesogens used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport or host materials in OLED devices due to its stable, conjugated structure.
• Polymer Modification: The carboxylic acid functionality allows for incorporation into specialty polymers to impart specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions and creating complex molecular libraries for screening.

Basic Information

Product Name	3-Biphenyl-3'-Fluoro-Acetic Acid
CAS No.	669713-86-4
Molecular Formula	C₁₄H₁₁FO₂
Molecular Weight	230.24 g/mol
Synonyms	[3-(3-Fluorophenyl)phenyl]acetic acid; 2-[3-(3-Fluorophenyl)phenyl]acetic acid; 3'-Fluoro-[1,1'-biphenyl]-3-acetic acid; 3-(3-Fluorobiphenyl)acetic acid; 3-Biphenyl-3'-fluoroacetic acid; (3'-Fluoro[1,1'-biphenyl]-3-yl)acetic acid; NSC 796080
EINECS	Contact for details

Quality Control

Every batch of 3-Biphenyl-3'-Fluoro-Acetic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support applications requiring material consistency under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, appropriate chemical-resistant secondary containment is advised.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.