Description

2-[(2-Fluorobenzyl)Thio]Acetohydrazide is a specialized organic building block featuring a fluorinated benzyl thioether and a reactive hydrazide functional group. This unique molecular architecture makes it a valuable intermediate for the synthesis of novel heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: The reactive hydrazide group allows for conjugation, making it useful for creating chemical probes to study enzyme function or protein interactions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or chemical resistance properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-[(2-Fluorobenzyl)Thio]Acetohydrazide
CAS No.	669705-47-9
Molecular Formula	C9H11FN2OS
Molecular Weight	214.26 g/mol
Synonyms	Acetic acid, 2-[(2-fluorophenyl)methyl]thio]-, hydrazide; 2-[(2-Fluorobenzyl)sulfanyl]acetohydrazide; N'-Acetyl-2-[(2-fluorobenzyl)thio]hydrazine; 2-(2-Fluorobenzylthio)acetohydrazide; Acetohydrazide, 2-[(2-fluorobenzyl)thio]-; 2-Fluorobenzylthioacetohydrazide
EINECS	Contact for details

Quality Control

Our 2-[(2-Fluorobenzyl)Thio]Acetohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.