Description

tert-Butyl 4-(4-Methoxy-4-Oxo-2-(Quinolin-3-Yl)But-2-En-1-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular structure integrating piperidine and quinoline moieties. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• API Synthesis: Used in multi-step organic synthesis for constructing complex molecular scaffolds essential for final Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing in pharmaceutical analysis.
• Custom Synthesis Building Block: Provides a versatile starting material for contract research organizations (CROs) and specialty chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	tert-Butyl 4-(4-Methoxy-4-Oxo-2-(Quinolin-3-Yl)But-2-En-1-Yl)Piperidine-1-Carboxylate
CAS No.	669075-95-0
Molecular Formula	C25H30N2O4
Molecular Weight	422.52 g/mol
Synonyms	1-Boc-4-[(2E)-4-Methoxy-4-oxo-2-(quinolin-3-yl)but-2-en-1-yl]piperidine; tert-Butyl 4-[(1E)-3-(methoxycarbonyl)-3-(quinolin-3-yl)prop-1-en-1-yl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(2E)-4-methoxy-4-oxo-2-(quinolin-3-yl)but-2-en-1-yl]piperidine; 3-Quinolineacrylic acid, 3-(3-methoxy-3-oxo-1-propen-1-yl)-, 1,1-dimethylethyl ester (related); BOC-Piperidine Quinoline Derivative; 669075-95-0; (2E)-1-(1-Boc-4-piperidinyl)-3-(3-quinolyl)-2-propen-1-one methyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Methoxy-4-Oxo-2-(Quinolin-3-Yl)But-2-En-1-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, to ensure compliance with stringent specifications suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.