Description

5-Benzo[1,3]Dioxol-5-Yl-Isoxazole-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused-ring isoxazole structure imparts specific biological and chemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in electronic applications due to its rigid, conjugated structure.
• Ligand and Catalyst Development: Employed in creating novel chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and Contract Research: A valuable reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.
• Custom Synthesis and Scale-Up: Supplied for custom manufacturing projects requiring this specific molecular scaffold for client-specific applications.

Basic Information

Item	Detail
Product Name	5-Benzo[1,3]Dioxol-5-Yl-Isoxazole-3-Carboxylic Acid
CAS No.	668971-47-9
Molecular Formula	C11H7NO5
Molecular Weight	233.18 g/mol
Synonyms	5-(1,3-Benzodioxol-5-yl)-1,2-oxazole-3-carboxylic acid; 5-(Benzo[d][1,3]dioxol-5-yl)isoxazole-3-carboxylic acid; 5-(1,3-Benzodioxol-5-yl)isoxazole-3-carboxylic acid; 3-Isoxazolecarboxylic acid, 5-(1,3-benzodioxol-5-yl)-; 668971-47-9; 5-(2H-1,3-Benzodioxol-5-yl)-3-isoxazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Benzo[1,3]Dioxol-5-Yl-Isoxazole-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling should be conducted under appropriate light-controlled conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.