Description

5-(4-(Trifluoromethyl)Phenyl)Isoxazole-3-Carboxylic Acid is a high-value, multifunctional heterocyclic building block featuring a trifluoromethylphenyl group and an isoxazole carboxylic acid moiety. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting inflammation, central nervous system (CNS) disorders, and oncology.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Incorporated into the design of advanced polymers and organic electronic materials to modify electronic properties and stability.
• Chemical Biology Probe: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(4-(Trifluoromethyl)Phenyl)Isoxazole-3-Carboxylic Acid
CAS No.	668970-85-2
Molecular Formula	C11H6F3NO3
Molecular Weight	257.17 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]-1,2-oxazole-3-carboxylic acid; 5-(4-Trifluoromethylphenyl)isoxazole-3-carboxylic acid; 3-Isoxazolecarboxylic acid, 5-[4-(trifluoromethyl)phenyl]-; 5-(p-Trifluoromethylphenyl)isoxazole-3-carboxylic acid; 668970-85-2; AI3-52375; CTK8G7230; ZINC000103079505; AKOS040745393; DB08299
EINECS	Contact for details

Quality Control

Our 5-(4-(Trifluoromethyl)Phenyl)Isoxazole-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.