Description

4-Bromo-2-Fluoromandelic Acid is a high-value fluorinated mandelic acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it indispensable for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the development of agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for CNS and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers with specific optical or chemical properties.

Basic Information

Product Name	4-Bromo-2-Fluoromandelic Acid
CAS No.	668970-55-6
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	2-Fluoro-4-bromomandelic acid; (RS)-4-Bromo-2-fluoromandelic acid; (±)-4-Bromo-2-fluoromandelic acid; α-Hydroxy-4-bromo-2-fluorophenylacetic acid; 4-Bromo-2-fluoro-α-hydroxybenzeneacetic acid; 4-Bromo-2-fluorobenzene glycolic acid; DL-4-Bromo-2-fluoromandelic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoromandelic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.