Description

8-Methoxy-5-Chloromethylquinolinehydrochloride is a versatile and high-value quinoline derivative, primarily serving as a critical pharmaceutical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). Its unique structure, featuring both methoxy and chloromethyl functional groups, makes it a key building block for constructing molecules with specific biological activity. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create new therapeutic agents and advanced crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based APIs, particularly for anti-malarial, anti-cancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the quinoline scaffold for targeted biological activity.
• Organic Synthesis Building Block: The reactive chloromethyl group allows for further functionalization, making it valuable for creating complex organic molecules in research settings.
• Material Science Research: Investigated as a monomer or precursor for the development of specialty polymers and advanced organic electronic materials.
• Biochemical Research: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical and pharmacological studies.

Basic Information

Product Name	8-Methoxy-5-Chloromethylquinolinehydrochloride
CAS No.	668275-75-0
Molecular Formula	C12H13Cl2NO
Molecular Weight	258.14 g/mol
Synonyms	5-(Chloromethyl)-8-methoxyquinoline hydrochloride; 8-Methoxy-5-(chloromethyl)quinoline hydrochloride; Quinoline, 5-(chloromethyl)-8-methoxy-, hydrochloride (1:1); 8-Methoxy-5-chloromethylquinoline HCl
EINECS	Contact for details

Quality Control

Our 8-Methoxy-5-Chloromethylquinolinehydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.