Description

1,3A-Methano-3Ah-Indene-3,8-Diol, Octahydro-8-(Hydroxymethyl)-7A-Methyl-, (1R,3R,3Ar,7Ar,8R)-Rel- (9Ci) is a high-purity, stereochemically defined polycyclic diol derivative, serving as a critical advanced intermediate in complex organic syntheses. Its precise stereochemistry and functional group arrangement make it an invaluable building block for the development of novel pharmaceutical compounds and fine chemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with specific biological activity or material properties.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in steroid-like or terpenoid-based drug discovery programs.
• Agrochemical Research: Used as a precursor in developing new generation pesticides and herbicides with enhanced selectivity and efficacy.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural product analogs, flavors, and fragrances.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and resins with unique thermal or mechanical properties.
• Catalyst Ligand Development: The diol and hydroxymethyl groups can be utilized to construct sophisticated chiral ligands for asymmetric catalysis.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and for contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	1,3A-Methano-3Ah-Indene-3,8-Diol, Octahydro-8-(Hydroxymethyl)-7A-Methyl-, (1R,3R,3Ar,7Ar,8R)-Rel- (9Ci)
CAS No.	667938-64-9
Molecular Formula	C15H26O3
Molecular Weight	254.37 g/mol
Synonyms	(1R,3R,3aR,7aR,8R)-Octahydro-8-(hydroxymethyl)-7a-methyl-1,3a-methano-3aH-indene-3,8-diol; rel-(1R,3R,3aR,7aR,8R)-Octahydro-8-(hydroxymethyl)-7a-methyl-1,3a-methano-3aH-indene-3,8-diol; 1,3a-Methano-3aH-indene-3,8-diol, octahydro-8-(hydroxymethyl)-7a-methyl-, (1R,3R,3aR,7aR,8R)-rel-; Polycyclic Diol Derivative CAS 667938-64-9; Advanced Chiral Diol Intermediate; Steroid-like Diol Synthon.
EINECS	Contact for details

Quality Control

Our 1,3A-Methano-3Ah-Indene-3,8-Diol, Octahydro-8-(Hydroxymethyl)-7A-Methyl-, (1R,3R,3Ar,7Ar,8R)-Rel- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.