Description

2-Chloro-6-Methyl-3-[1-(Methylsulfonyl)-3-(2-Thienyl)-4,5-Dihydro-1H-Pyrazol-5-Yl]Quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug molecules, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Development & Scale-Up: Serves as a critical material for optimizing synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the custom synthesis of complex molecules for client projects.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	2-Chloro-6-Methyl-3-[1-(Methylsulfonyl)-3-(2-Thienyl)-4,5-Dihydro-1H-Pyrazol-5-Yl]Quinoline
CAS No.	667898-83-1
Molecular Formula	C19H18ClN3O2S2
Molecular Weight	419.95 g/mol
Synonyms	2-Chloro-6-methyl-3-[1-(methylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl]quinoline; 2-Chloro-6-methyl-3-[1-(methylsulfonyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-5-yl]quinoline; Quinoline, 2-chloro-6-methyl-3-[1-(methylsulfonyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-5-yl]-; CAS 667898-83-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methyl-3-[1-(Methylsulfonyl)-3-(2-Thienyl)-4,5-Dihydro-1H-Pyrazol-5-Yl]Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.