Description

2-Chloro-6-Ethoxy-3-(1-(Methylsulfonyl)-3-(p-Tolyl)-4,5-Dihydro-1H-Pyrazol-5-Yl)Quinoline is a sophisticated heterocyclic organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its complex molecular architecture, featuring fused quinoline and dihydropyrazole rings, makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

This compound is designed for high-value synthetic applications, particularly in regulated industries where precision and purity are paramount.

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile chemical scaffold.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Research: Potential intermediate in the development of new generation crop protection agents and pesticides.
• Material Science: Exploration of its use in creating organic electronic materials or specialty polymers with unique properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Chloro-6-Ethoxy-3-(1-(Methylsulfonyl)-3-(p-Tolyl)-4,5-Dihydro-1H-Pyrazol-5-Yl)Quinoline
CAS No.	667898-78-4
Molecular Formula	C22H22ClN3O3S
Molecular Weight	443.95 g/mol
Synonyms	2-Chloro-6-ethoxy-3-[1-(methylsulfonyl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-5-yl]quinoline; 2-Chloro-6-ethoxy-3-[1-(methylsulfonyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-5-yl]quinoline; 3-(1-Methanesulfonyl-3-p-tolyl-4,5-dihydro-1H-pyrazol-5-yl)-2-chloro-6-ethoxyquinoline; Quinoline, 2-chloro-6-ethoxy-3-[1-(methylsulfonyl)-3-(4-methylphenyl)-4,5-dihydro-1H-pyrazol-5-yl]-; CAS 667898-78-4
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-6-Ethoxy-3-(1-(Methylsulfonyl)-3-(p-Tolyl)-4,5-Dihydro-1H-Pyrazol-5-Yl)Quinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development work. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support development under quality guidelines appropriate for preclinical and clinical stage materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.