Description

8-Chloro-2-(2-Methylphenyl)Quinoline-4-Carboxylic Acid is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloroquinoline and phenylcarboxylic acid moieties, makes it a versatile intermediate for creating complex molecules with targeted properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for applications in oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a monomer or functional additive in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.

Basic Information

Product Name	8-Chloro-2-(2-Methylphenyl)Quinoline-4-Carboxylic Acid
CAS No.	667437-81-2
Molecular Formula	C₁₇H₁₂ClNO₂
Molecular Weight	297.74 g/mol
Synonyms	8-Chloro-2-(o-tolyl)quinoline-4-carboxylic acid; 2-(2-Methylphenyl)-8-chloroquinoline-4-carboxylic acid; 8-Chloro-2-(2-methylphenyl)-4-quinolinecarboxylic acid; 667437-81-2; Quinoline-4-carboxylic acid, 8-chloro-2-(2-methylphenyl)-; 8-Chloro-2-(2-methylphenyl)quinoline-4-carboxylicacid; 8-Chloro-2-(o-methylphenyl)-4-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and synthesis. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to a quality management system to ensure supply reliability and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.