Description

8-Chloro-2-Pyridin-3-Ylquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline-pyridine hybrid structure. This compound matters as a critical building block in the synthesis of novel, targeted therapeutic agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a ligand or building block for metal-organic frameworks (MOFs) and functional organic materials.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing.

Basic Information

Product Name	8-Chloro-2-Pyridin-3-Ylquinoline-4-Carboxylic Acid
CAS No.	667436-24-0
Molecular Formula	C15H9ClN2O2
Molecular Weight	284.70 g/mol
Synonyms	8-Chloro-2-(pyridin-3-yl)quinoline-4-carboxylic acid; 8-Chloro-2-(3-pyridinyl)-4-quinolinecarboxylic acid; 667436-24-0; Quinoline-4-carboxylic acid, 8-chloro-2-(3-pyridinyl)-; 2-(3-Pyridinyl)-8-chloro-4-quinolinecarboxylic acid; 8-Chloro-2-(3-pyridyl)quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Pyridin-3-Ylquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.