Description

8-Methyl-2-(5-Methylthien-2-Yl)Quinoline-4-Carboxylic Acid is a high-purity, synthetically derived organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its unique quinoline-thiophene hybrid structure makes it a valuable scaffold for constructing novel active pharmaceutical ingredients (APIs) with targeted therapeutic properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its fused ring system for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening.
• Material Science: Investigated as a potential monomer or dopant in the development of organic electronic materials due to its conjugated structure.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for fundamental research in medicinal and synthetic chemistry.

Basic Information

Product Name	8-Methyl-2-(5-Methylthien-2-Yl)Quinoline-4-Carboxylic Acid
CAS No.	667412-63-7
Molecular Formula	C₁₆H₁₃NO₂S
Molecular Weight	283.35 g/mol
Synonyms	8-Methyl-2-(5-methyl-2-thienyl)-4-quinolinecarboxylic acid; 2-(5-Methylthiophen-2-yl)-8-methylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 8-methyl-2-(5-methyl-2-thienyl)-; 667412-63-7; 8-Methyl-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 8-Methyl-2-(5-Methylthien-2-Yl)Quinoline-4-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.