Description

8-Chloro-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex small molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific enzyme or receptor families.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• API Synthesis: Used in the development and scale-up production of Active Pharmaceutical Ingredients (APIs) with quinoline and pyridine core structures.
• Biochemical Tool Compound: Potential use in the development of biochemical probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.

Basic Information

Product Name	8-Chloro-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid
CAS No.	667412-53-5
Molecular Formula	C15H9ClN2O2
Molecular Weight	284.70 g/mol
Synonyms	8-Chloro-2-(pyridin-4-yl)quinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 8-chloro-2-(4-pyridinyl)-; 8-Chloro-2-(4-pyridinyl)-4-quinolinecarboxylic acid; 667412-53-5; 8-Chloro-2-(4-pyridyl)quinoline-4-carboxylic acid; 8-Chloro-2-(4-pyridinyl)quinoline-4-carboxylic acid; 8-Chloro-2-(pyridin-4-yl)-4-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Pyridin-4-Ylquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.