Description

4-Bromomethyl-6-(2-Methoxybiphenyl)-2,2,-Dimethyl-1,2-Dihydroquinoline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Organic Synthesis Building Block: Used in research laboratories for constructing complex quinoline and biphenyl-based molecular frameworks.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the discovery of new biologically active molecules.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Bromomethyl-6-(2-Methoxybiphenyl)-2,2,-Dimethyl-1,2-Dihydroquinoline
CAS No.	666726-33-6
Molecular Formula	C26H24BrNO
Molecular Weight	446.38 g/mol
Synonyms	4-(Bromomethyl)-6-[2-(methoxyphenyl)phenyl]-2,2-dimethyl-1,2-dihydroquinoline; 6-(2-Methoxybiphenyl-4-yl)-2,2-dimethyl-1,2-dihydroquinoline-4-ylmethyl Bromide; 4-Bromomethyl-6-(2'-methoxybiphenyl-2-yl)-2,2-dimethyl-1,2-dihydroquinoline; BMTQ Intermediate; CAS 666726-33-6
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-6-(2-Methoxybiphenyl)-2,2,-Dimethyl-1,2-Dihydroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.