Description

3-Quinolinecarboxylic Acid, 7-[4-[[(4-Chlorobenzoyl)Amino]Thioxomethyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the antibacterial and antimicrobial fields. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in synthesizing next-generation quinolone-based drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone antibiotic candidates.
• Antimicrobial Research: Used in biological studies to develop new agents against drug-resistant bacterial strains.
• Chemical Synthesis: Serves as a precursor for creating more complex molecules with potential pharmacological activity.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and institutes for studying structure-activity relationships (SAR) in medicinal chemistry.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[4-[[(4-Chlorobenzoyl)Amino]Thioxomethyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	663938-44-1
Molecular Formula	C24H21ClFN4O3S
Molecular Weight	508.97 g/mol
Synonyms	7-[4-[[(4-Chlorobenzoyl)Amino]Thioxomethyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid; 1-Cyclopropyl-6-fluoro-7-(4-((4-chlorobenzoyl)carbamothioyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Gatifloxacin Intermediate; Advanced Fluoroquinolone Intermediate; Quinolone Carboxylic Acid Derivative; AM-1155 Intermediate (related); LB20304a Intermediate (related)
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; handling under an inert atmosphere is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.