Description

4H-Pyrido[1,2-A]Pyrimidin-4-One, 7-Methyl-2-(4-Morpholinyl)-9-[1-(Phenylamino)Ethyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of small molecule kinase inhibitors due to its pyridopyrimidinone structure.
• Medicinal Chemistry Building Block: Used in combinatorial chemistry and parallel synthesis for creating focused libraries for high-throughput screening.
• Chemical Biology Probes: Employed in the development of molecular probes to study specific biological processes and protein functions.
• Contract Research & Development (CRO/CDMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	4H-Pyrido[1,2-A]Pyrimidin-4-One, 7-Methyl-2-(4-Morpholinyl)-9-[1-(Phenylamino)Ethyl]-
CAS No.	663619-89-4
Molecular Formula	C20H24N4O2
Molecular Weight	352.43 g/mol
Synonyms	7-Methyl-2-morpholino-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one; 9-[1-(Anilino)ethyl]-7-methyl-2-(4-morpholinyl)-4H-pyrido[1,2-a]pyrimidin-4-one; 663619-89-4; UNII-8W8T171F1I; 8W8T171F1I; BDBM50364695; AKOS009158046; A-867744; A 867744; A867744. (Z)-isomer of A-867744.
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard high-purity grade meets the exacting requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.