Description

Ethyl 4,8-Dichloro-2-(Methylthio)Quinoline-3-Carboxylate is a high-purity, multi-functional quinoline derivative serving as a critical advanced pharmaceutical intermediate and versatile chemical building block. Its unique halogenated and thioether-substituted structure makes it indispensable for synthesizing complex molecules with targeted biological activity. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents, including fungicides and herbicides, leveraging its heterocyclic core.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and specialty polymers due to its electron-deficient quinoline scaffold.
• Chemical Biology Probes: Serves as a core structure for creating fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research purposes.
• Fine Chemical Manufacturing: Intermediate for producing dyes, pigments, and other high-value specialty chemicals requiring a functionalized quinoline moiety.

Basic Information

Product Name	Ethyl 4,8-Dichloro-2-(Methylthio)Quinoline-3-Carboxylate
CAS No.	662138-33-2
Molecular Formula	C₁₃H₁₁Cl₂NO₂S
Molecular Weight	316.20 g/mol
Synonyms	Ethyl 4,8-dichloro-2-(methylsulfanyl)quinoline-3-carboxylate; 2-(Methylthio)-4,8-dichloroquinoline-3-carboxylic Acid Ethyl Ester; 4,8-Dichloro-2-(methylthio)quinoline-3-carboxylic Acid Ethyl Ester; Quinoline-3-carboxylic acid, 4,8-dichloro-2-(methylthio)-, ethyl ester; CAS 662138-33-2
EINECS	Contact for details

Quality Control

Our production of Ethyl 4,8-Dichloro-2-(Methylthio)Quinoline-3-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure consistency and meet exacting customer specifications. Certificates of Analysis (COA) detailing all critical parameters are provided and traceability is maintained for full quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.