Description

4-Bromo-2-Fluoro-5-Nitrophenol is a halogenated nitrophenol derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromine, fluorine, and nitro substituents on a phenolic ring, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides, where the fluorine and nitro groups enhance biological activity.
• Material Science Research: Used in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized azo dyes and colorants.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Nitrophenol
CAS No.	661463-12-3
Molecular Formula	C6H3BrFNO3
Molecular Weight	236.00 g/mol
Synonyms	5-Nitro-4-bromo-2-fluorophenol; 2-Fluoro-4-bromo-5-nitrophenol; 4-Bromo-2-fluoro-5-nitro-1-hydroxybenzene; Phenol, 4-bromo-2-fluoro-5-nitro-; 1-Hydroxy-4-bromo-2-fluoro-5-nitrobenzene; BFNP (abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.