Description

Endo-3-(4-Methylbenzoyl)-7-Oxabicyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting neurological or inflammatory pathways.
• Organic Synthesis Building Block: Used in research and development for constructing complex molecular architectures due to its reactive carboxylic acid and ketone functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Used as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	Endo-3-(4-Methylbenzoyl)-7-Oxabicyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid
CAS No.	658704-71-3
Molecular Formula	C16H16O4
Molecular Weight	272.30 g/mol
Synonyms	7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(4-methylbenzoyl)-, endo-, exo-; 3-(p-Toluoyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid; Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-(4-methylbenzoyl)-7-oxa-, (1R,2S,3R,4S)-rel-; (1R,2S,3R,4S)-3-(4-Methylbenzoyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid; Advanced Pharmaceutical Intermediate 658704-71-3
EINECS	Contact for details

Quality Control

Our production of Endo-3-(4-Methylbenzoyl)-7-Oxabicyclo[2.2.1]Heptane-Exo-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.