Description

(3-Fluoro-4-Nitrophenyl)Carbamic Acid tert-Butyl Ester is a high-purity, protected aniline derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine and nitro substituents enable precise structural modifications. It is primarily needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in medicinal chemistry and custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the bioactivity of the fluoronitroaniline scaffold.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile reactive sites.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.
• Chemical Biology Probes: Can be utilized to create labeled compounds or probes for studying biological mechanisms.
• Material Science Research: Potential intermediate for synthesizing specialty polymers or advanced organic materials with specific electronic properties.

Basic Information

Product Name	(3-Fluoro-4-Nitrophenyl)Carbamic Acid tert-Butyl Ester
CAS No.	658700-15-3
Molecular Formula	C11H13FN2O4
Molecular Weight	256.23 g/mol
Synonyms	tert-Butyl (3-fluoro-4-nitrophenyl)carbamate; N-Boc-3-fluoro-4-nitroaniline; Boc-3-fluoro-4-nitroaniline; Carbamic acid, N-(3-fluoro-4-nitrophenyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-(3-fluoro-4-nitrophenyl)carbamate; (3-Fluoro-4-nitro-phenyl)-carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-3-fluoro-4-nitroaniline
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-Nitrophenyl)Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.