Description

5-Chloro-2-Fluorobenzohydrazide is a high-purity fluorinated aromatic hydrazide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, enabling the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for improved bioavailability and environmental stability.
• Heterocyclic Chemistry: Fundamental building block for constructing pyrazole, triazole, and other nitrogen-containing heterocycles via cyclization reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value fine chemicals and dyes.

Basic Information

Product Name	5-Chloro-2-Fluorobenzohydrazide
CAS No.	657424-44-7
Molecular Formula	C7H6ClFN2O
Molecular Weight	188.59 g/mol
Synonyms	5-Chloro-2-fluorobenzoic acid hydrazide; 2-Fluoro-5-chlorobenzohydrazide; Benzoic acid, 5-chloro-2-fluoro-, hydrazide; (5-Chloro-2-fluorophenyl)formohydrazide; 5-Chloro-2-fluorobenzoylhydrazine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluorobenzohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) with full traceability are provided to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.