Description

1H-Cyclopropa[G]Quinazoline (9Ci) is a specialized fused heterocyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. This high-purity building block is valued for its unique cyclopropane-fused quinazoline scaffold, which serves as a critical precursor for developing novel bioactive molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for lead optimization and the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of new active ingredients for crop protection products, leveraging its complex heterocyclic structure.
• Chemical Biology Probe: Employed as a scaffold in fragment-based drug discovery and for studying protein-ligand interactions.
• Material Science: Investigated as a building block for advanced organic electronic materials due to its conjugated system.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies in synthetic organic chemistry and heterocycle construction.

Basic Information

Product Name	1H-Cyclopropa[G]Quinazoline (9Ci)
CAS No.	656231-71-9
Molecular Formula	C11H8N2
Molecular Weight	168.20 g/mol
Synonyms	1H-Cyclopropa[g]quinazoline; Cyclopropa[g]quinazoline, 1H-; 1H-Cyclopropa[G]Quinazoline; 1H-Cyclopropa[g]quinazoline (9CI); Quinazoline, 1H-cyclopropa[g]-; 656231-71-9
EINECS	Contact for details

Quality Control

Our 1H-Cyclopropa[G]Quinazoline (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles for advanced intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to prevent degradation. Handle and store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.