Description

8-Bromo-5-Fluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated quinoline scaffold, which serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinoline-based drug candidates, particularly in antimicrobial, anticancer, and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Material Science Research: Investigated as a precursor for functional organic materials, including ligands for metal-organic frameworks (MOFs) and optoelectronic materials.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	8-Bromo-5-Fluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	655236-28-5
Molecular Formula	C₁₃H₉BrFNO₃
Molecular Weight	326.12 g/mol
Synonyms	Ethyl 8-Bromo-5-Fluoro-4-Hydroxyquinoline-3-Carboxylate; 8-Bromo-5-Fluoro-4-Hydroxy-3-Quinolinecarboxylic Acid Ethyl Ester; 655236-28-5; 8-Br-5-F-4-OH-Quinoline-3-COOEt; 3-Quinolinecarboxylic Acid, 8-Bromo-5-Fluoro-4-Hydroxy-, Ethyl Ester
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Fluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.