Description

8-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline is a high-purity, multi-functional halogenated quinoline derivative serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in the unique reactivity imparted by the bromo, chloro, and trifluoromethyl substituents, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to build novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research pipelines.
• Agrochemical Active Ingredient Development: Used to construct complex heterocyclic cores for new-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, such as OLED emitters and charge-transport layers.
• Ligand and Catalyst Synthesis: Utilized in the preparation of specialized nitrogen-containing ligands for transition metal catalysis.
• Fluorinated Compound Library Synthesis: A valuable scaffold for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Academic and R&D Laboratories: Employed in methodological studies and the exploration of new cross-coupling and functionalization reactions.

Basic Information

Product Name	8-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline
CAS No.	655235-61-3
Molecular Formula	C10H4BrClF3N
Molecular Weight	310.50 g/mol
Synonyms	8-Bromo-4-chloro-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-8-bromo-4-chloroquinoline; Quinoline, 8-bromo-4-chloro-2-(trifluoromethyl)-; 655235-61-3; 8-Bromo-4-chloro-2-trifluoromethylquinoline; 4-Chloro-8-bromo-2-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-2-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our commitment to quality assurance ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.