Description

4-(Phenylethynyl)Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique piperidine scaffold functionalized with a phenylethynyl group, which is critical for modulating biological activity and physicochemical properties in drug discovery. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Reagent: Used in cross-coupling reactions, click chemistry, and as a precursor for more complex heterocyclic compounds.
• Agrochemical Research: Serves as a structural component in the development of new pesticides and herbicides.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Material Science: A potential monomer or additive in the development of specialty polymers with tailored properties.

Basic Information

Product Name	4-(Phenylethynyl)Piperidine Hydrochloride
CAS No.	654663-00-0
Molecular Formula	C13H15N·HCl
Molecular Weight	221.73 g/mol
Synonyms	4-(Phenylethynyl)piperidine HCl; 4-(2-Phenylethynyl)piperidine hydrochloride; 1-(2-Phenylethynyl)-4-piperidine hydrochloride; Piperidine, 4-(2-phenylethynyl)-, hydrochloride; 4-(Phenylethynyl)piperidine HCl salt; 4-Ethynylphenylpiperidine hydrochloride; 654663-00-0
EINECS	Contact for details

Quality Control

Our 4-(Phenylethynyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.