Description

Neocuproine Hydrate, 99% is a high-purity, water-containing form of the specific copper(I)-chelating reagent, 2,9-dimethyl-1,10-phenanthroline. This compound matters as a highly selective chromogenic agent for the spectrophotometric determination of copper(I) ions, offering superior sensitivity and specificity over other chelators like bathocuproine. It is essential for researchers and quality control laboratories in sectors requiring precise trace metal analysis, including pharmaceutical development, environmental monitoring, and industrial chemical manufacturing.

Application

• Spectrophotometric Copper Assay: Primary application as a selective chromogenic reagent for the colorimetric detection and quantification of cuprous (Cu(I)) ions in solution.
• Biochemical Research: Used in studies of copper-containing enzymes and proteins to sequester or quantify biologically available copper.
• Pharmaceutical Analysis: Employed in purity testing and method development for APIs and drug products where copper is a potential impurity.
• Environmental Testing: Detection of trace copper in water, soil, and industrial effluent samples for regulatory compliance.
• Food & Beverage Quality Control: Analysis of copper content in foodstuffs, nutritional supplements, and beverages.
• Material Science: Research into copper catalysis and the synthesis of copper-based nanomaterials.
• Diagnostic Reagent Formulation: A key component in the formulation of clinical chemistry reagents for copper level testing.

Basic Information

Product Name	Neocuproine Hydrate, 99%
CAS No.	654054-57-6
Molecular Formula	C₁₄H₁₂N₂·xH₂O
Molecular Weight	208.26 (anhydrous basis)
Synonyms	2,9-Dimethyl-1,10-phenanthroline Hydrate; 2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline Hydrate (common misnomer); Neocuproine Monohydrate; Cuprous Ion Specific Indicator; Neocuproin Hydrate; Cuproine Derivative; BCS (Bathocuproinedisulfonic acid) alternative; NC Hydrate
EINECS	Contact for details

Quality Control

Our Neocuproine Hydrate, 99% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standard of 99% minimum assay (on an anhydrous basis) and is free from significant interfering impurities. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic; ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0% (anhydrous basis)
Water Content (KF)	Reported on COA
Heavy Metals (as Pb)	< 20 ppm
Residue on Ignition	< 0.1%
Solubility Test	Clear, yellow solution in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.