Description

trans-1,2,3,3A,5,9B-Hexahydro-Pyrrolo[3,4-C]Quinolin-4-One CAS NO 653598-67-5 is a high-purity, advanced pharmaceutical intermediate belonging to the fused polycyclic heterocycle class. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Used in research and development for constructing complex polycyclic molecular architectures due to its rigid fused ring system.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new biologically active molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Reference Standard: Used as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Item	Details
Product Name	trans-1,2,3,3A,5,9B-Hexahydro-Pyrrolo[3,4-C]Quinolin-4-One
CAS No.	653598-67-5
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	trans-Hexahydropyrrolo[3,4-c]quinolin-4-one; (3aR,9bR)-2,3,3a,5,9,9b-Hexahydro-1H-pyrrolo[3,4-c]quinolin-4-one; Pyrrolo[3,4-c]quinolin-4(1H)-one, hexahydro-, trans-; 653598-67-5; BCP31989; A1-008/31509055; SCHEMBL2184941; ZINC000004259777
EINECS	Contact for details

Quality Control

Our trans-1,2,3,3A,5,9B-Hexahydro-Pyrrolo[3,4-C]Quinolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.