Description

1H-2-Benzopyran-1-One,3-[(2S,3R)-3-Ethyloxiranyl]-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate (API intermediate) with the CAS registry number 653597-82-1. This compound is valued for its precise chiral structure, which is critical for synthesizing active pharmaceutical ingredients (APIs) with high enantiomeric purity and efficacy. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct molecules with specific three-dimensional configurations.
• Process Chemistry R&D: Serves as a critical starting material or intermediate in route scouting and optimization for new chemical entities (NCEs).
• Reference Standard: Used as an analytical standard for method development and quality control in API manufacturing.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals requiring high chiral purity.

Basic Information

Product Name	1H-2-Benzopyran-1-One,3-[(2S,3R)-3-Ethyloxiranyl]-(9Ci)
CAS No.	653597-82-1
Molecular Formula	C13H14O3
Molecular Weight	218.25 g/mol
Synonyms	3-[(2S,3R)-3-Ethyloxiranyl]-1H-2-benzopyran-1-one; (2S,3R)-3-Ethyl-3-(1-oxo-1H-isochromen-3-yl)oxirane; 3-((2S,3R)-3-Ethyloxiran-2-yl)-1H-isochromen-1-one; 653597-82-1; 1H-2-Benzopyran-1-one, 3-[(2S,3R)-3-ethyloxiranyl]-; 3-[(2S,3R)-3-Ethyl-2-oxiranyl]-1H-2-benzopyran-1-one
EINECS	Contact for details

Quality Control

Our 1H-2-Benzopyran-1-One,3-[(2S,3R)-3-Ethyloxiranyl]-(9Ci) is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.