Description

Bis(4-Nitrobenzyl)Malonic Acid is a specialized organic compound featuring two 4-nitrobenzyl groups attached to a malonic acid core. This structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists working in advanced organic synthesis. The compound, identified by CAS No. 653306-99-1, is essential for constructing target molecules with specific nitro-aromatic functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring nitrobenzyl-protected groups.
• Organic Synthesis Reagent: Used in multi-step synthetic routes for constructing complex organic frameworks, including dyes, pigments, and advanced materials.
• Chemical Research & Development: A crucial starting material in academic and industrial R&D labs for exploring new chemical reactions and methodologies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where precise molecular architecture is required.
• Protecting Group Chemistry: The nitrobenzyl moiety can act as a protecting group for carboxylic acids or other functional groups in complex syntheses.

Basic Information

Product Name	Bis(4-Nitrobenzyl)Malonic Acid
CAS No.	653306-99-1
Molecular Formula	C₁₇H₁₄N₂O₈
Molecular Weight	374.30 g/mol
Synonyms	Bis(p-Nitrobenzyl)malonic Acid; Di(4-nitrobenzyl)malonate; Malonic Acid, Bis(4-nitrobenzyl) Ester; 2,2-Bis(4-nitrobenzyl)malonic Acid; 4-Nitrobenzyl Malonate; 1,1'-(1,3-Dioxo-1,3-propanediyl)bis(4-nitrobenzene); Propanedioic Acid, Bis(4-nitrobenzyl) Ester; (4-Nitrobenzyl) Malonic Acid Ester
EINECS	Contact for details

Quality Control

Our Bis(4-Nitrobenzyl)Malonic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, confirming compliance with your specific research or production requirements. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.