Description

Spiro[6-Oxabicyclo[3.1.0]Hexane-3,2-Oxirane] (9Ci) is a high-purity, specialized spirocyclic oxirane compound with the CAS number 652142-48-8. This molecule is valued for its unique strained-ring structure, which makes it a versatile and reactive intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those with complex polycyclic or spirocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactivity to introduce oxirane functional groups.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and coatings with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for cycloaddition reactions and ring-opening polymerizations to create novel heterocyclic compounds.
• Ligand and Catalyst Development: Utilized as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Spiro[6-Oxabicyclo[3.1.0]Hexane-3,2-Oxirane] (9Ci)
CAS No.	652142-48-8
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	Spiro[6-oxabicyclo[3.1.0]hexane-3,2'-oxirane]; 3,7-Dioxatricyclo[4.1.0.0²,⁴]heptane; Oxaspiro[2.3]hexane-5,6-epoxide; 5,6-Epoxyoxaspiro[2.3]hexane; 2-Oxaspiro[3.2]hexane-1,3-dioxide (incorrect but common misnomer); Spiro-oxirane bicyclic ether
EINECS	Contact for details

Quality Control

Our Spiro[6-Oxabicyclo[3.1.0]Hexane-3,2-Oxirane] (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its reactive epoxide moiety, it should be stored separately from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.