Description

Spiro[Cyclopropane-1,5-[5H]Inden]-7(6H)-One, 6-Hydroxy-2,4,6-Trimethyl-, (6S)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused-ring structure, featuring a cyclopropane and indanone moiety, makes it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Material Science Research: Serves as a precursor for developing novel organic frameworks, ligands for catalysis, or liquid crystal materials.
• Asymmetric Catalysis: Employed as a starting material or ligand precursor in the development of new chiral catalysts for enantioselective reactions.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process optimization for complex organic molecule manufacturing.

Basic Information

Product Name	Spiro[Cyclopropane-1,5-[5H]Inden]-7(6H)-One, 6-Hydroxy-2,4,6-Trimethyl-, (6S)- (9Ci)
CAS No.	652134-40-2
Molecular Formula	C14H16O2
Molecular Weight	216.28 g/mol
Synonyms	(6S)-6-Hydroxy-2,4,6-trimethylspiro[cyclopropane-1,5'-inden]-7'(6'H)-one; (6S)-6-Hydroxy-2,4,6-trimethyl-1-oxaspiro[2.5]octa-4,7-dien-8-one (related bicyclic representation); 6-Hydroxy-2,4,6-trimethylspiro[cyclopropane-1,5-inden]-7(6H)-one, (6S)-; Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 6'-hydroxy-2',4',6'-trimethyl-, (6'S)-; Chiral spirocyclic indanone derivative; (S)-enantiomer of trimethylhydroxy spiroindenone.
EINECS	Contact for details

Quality Control

Every batch of Spiro[Cyclopropane-1,5-[5H]Inden]-7(6H)-One, 6-Hydroxy-2,4,6-Trimethyl-, (6S)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.