Description

1(3Ah)-Pentalenone, 4,5,6,6A-Tetrahydro-2,3A,4-Trihydroxy-3-(2-Propenyl)-, (3Ar,4S,6Ar)- (9Ci) is a complex, stereochemically defined pentalenone derivative that serves as a valuable advanced intermediate in organic synthesis. Its intricate polycyclic structure with multiple chiral centers makes it a critical building block for the development of novel, high-value chemical entities. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of natural product analogs.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in complex molecule synthesis.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for creating compound libraries to explore new biological targets and structure-activity relationships (SAR).
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total or semi-synthesis of complex natural products with pentalenone or related terpenoid skeletons.
• Process Chemistry Development: Employed in route scouting and optimization studies for the scalable production of target molecules in pilot plants.
• Chemical Biology Probes: Utilized to develop specialized molecular probes for studying enzyme mechanisms or cellular pathways.
• Academic & Institutional Research: Fundamental research tool in organic chemistry departments for methodology development and stereochemical studies.

Basic Information

Product Name	1(3Ah)-Pentalenone, 4,5,6,6A-Tetrahydro-2,3A,4-Trihydroxy-3-(2-Propenyl)-, (3Ar,4S,6Ar)- (9Ci)
CAS No.	652133-04-5
Molecular Formula	C13H18O4
Molecular Weight	238.28 g/mol
Synonyms	(3aR,4S,6aR)-4,5,6,6a-Tetrahydro-2,3a,4-trihydroxy-3-(prop-2-en-1-yl)-1(3aH)-pentalenone; 4,5,6,6a-Tetrahydro-2,3a,4-trihydroxy-3-(2-propenyl)-1(3aH)-pentalenone, (3aR,4S,6aR)-; Pentalenone derivative 652133-04-5; 3-Allyl-4,5,6,6a-tetrahydro-2,3a,4-trihydroxy-1(3aH)-pentalenone (stereospecific); (3aR,4S,6aR)-3-(Allyl)-4,5,6,6a-tetrahydro-2,3a,4-trihydroxy-1(3aH)-pentalenone
EINECS	Contact for details

Quality Control

Our production of this high-purity synthetic intermediate adheres to stringent quality management protocols. Every batch is characterized using advanced analytical techniques to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing specifications for assay, chiral purity, and key impurities. Our quality systems are designed to support cGMP-compliant applications in pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.