Description

Benzoic Acid, 4-(2-Fluoroethoxy)-2-Hydroxy- (9Ci) is a fluorinated derivative of salicylic acid, offering a unique combination of phenolic and benzoic acid functionalities with an ether-linked fluoroalkyl chain. This structural profile makes it a valuable advanced pharmaceutical intermediate for the synthesis of novel active compounds, particularly in drug discovery programs targeting inflammation and metabolic disorders. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorinated alkoxy substituents on drug potency and metabolic stability.
• Chemical Synthesis: Serves as a precursor for more complex fluorinated organic compounds in academic and industrial research settings.
• Material Science: Potential monomer or additive in the development of specialty polymers with specific surface properties.

Basic Information

Product Name	Benzoic Acid, 4-(2-Fluoroethoxy)-2-Hydroxy- (9Ci)
CAS No.	651331-95-2
Molecular Formula	C9H9FO4
Molecular Weight	200.16 g/mol
Synonyms	2-Hydroxy-4-(2-fluoroethoxy)benzoic acid; 4-(2-Fluoroethoxy)salicylic acid; 5-Fluoroethoxy-2-hydroxybenzoic acid; 2-Hydroxy-4-(β-fluoroethoxy)benzoic acid; Benzoic acid, 2-hydroxy-4-(2-fluoroethoxy)-; 4-(2-Fluoroethoxy)-2-hydroxybenzoic acid; Salicylic acid, 4-(2-fluoroethoxy)-
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 4-(2-Fluoroethoxy)-2-Hydroxy- (9Ci) adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.