Description

3-Acetyl-7-Chloroquinolin-4(1H)-One is a specialized quinoline derivative that serves as a crucial advanced intermediate in organic synthesis. Its molecular structure, featuring both acetyl and chloro substituents, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting infectious diseases or with anti-inflammatory properties.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Serves as a monomer or precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of complex quinoline-based dyes and colorants.

Basic Information

Product Name	3-Acetyl-7-Chloroquinolin-4(1H)-One
CAS No.	651331-06-5
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	7-Chloro-3-acetyl-4-hydroxyquinoline; 3-Acetyl-7-chloro-4(1H)-quinolinone; 7-Chloro-3-acetyl-1,4-dihydro-4-oxoquinoline; 3-Acetyl-7-chloro-1H-quinolin-4-one; 4-Hydroxy-7-chloro-3-quinolinecarboxaldehyde, 3-acetyl derivative; 651331-06-5; 3-Acetyl-7-chloro-4-quinolone
EINECS	Contact for details

Quality Control

Every batch of 3-Acetyl-7-Chloroquinolin-4(1H)-One is produced and tested under a strict quality management system. We ensure high purity and consistent performance suitable for demanding research and scale-up applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.