Description

1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene is a high-value, multi-functional organic intermediate featuring a unique combination of a bromoaryl group and a trifluoroethylsulfonyl moiety. This compound matters for its role as a versatile building block in advanced synthesis, enabling the introduction of both halogen and electron-withdrawing sulfone functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the sulfonyl and halogen groups.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal and chemical resistance.
• Ligand & Catalyst Development: Employed in the creation of sophisticated ligands for transition metal catalysis and organocatalysis.
• Fluorochemical Research: A valuable substrate for studying the effects of the trifluoroethyl group on molecular properties and reactivity.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene
CAS No.	648905-23-1
Molecular Formula	C8H6BrF3O2S
Molecular Weight	303.10 g/mol
Synonyms	4-Bromo-α,α,α-trifluoroethylsulfonylbenzene; p-Bromophenyl 2,2,2-trifluoroethyl sulfone; 1-Bromo-4-(2,2,2-trifluoroethanesulfonyl)benzene; (4-Bromophenyl)(2,2,2-trifluoroethyl) sulfone; 4-Bromophenyl trifluoroethyl sulfone; 648905-23-1; Benzene, 1-bromo-4-[(2,2,2-trifluoroethyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.