Description

4-Aminoquinazoline-6-Carbaldehyde is a high-value, multi-functional heterocyclic building block with significant synthetic utility. This compound is a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to construct complex quinazoline-based molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small molecule kinase inhibitors for oncology and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and fungicides based on the quinazoline scaffold.
• Chemical Biology Probes: Serves as a versatile handle for creating molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Building Block: The aldehyde and amine functional groups allow for diverse chemical transformations, including condensation and cyclization reactions.
• Material Science Research: Potential precursor for the synthesis of organic ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	4-Aminoquinazoline-6-Carbaldehyde
CAS No.	648449-11-0
Molecular Formula	C9H7N3O
Molecular Weight	173.17 g/mol
Synonyms	6-Formyl-4-quinazolinamine; 4-Amino-6-quinazolinecarboxaldehyde; 4-Amino-quinazoline-6-carbaldehyde; Quinazoline-6-carboxaldehyde, 4-amino-; 4-Amino-6-formylquinazoline; 6-Aldehyde-4-aminoquinazoline; 4-Aminoquinazoline-6-aldehyde
EINECS	Contact for details

Quality Control

Our 4-Aminoquinazoline-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.