Description

4-Chloroquinazoline-6-Carbaldehyde is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the chloro group and the aldehyde moiety—which enable precise and versatile derivatization for creating complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used to construct novel herbicide and fungicide candidates by functionalizing the quinazoline core.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive materials.
• Chemical Biology: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A versatile starting material for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	4-Chloroquinazoline-6-Carbaldehyde
CAS No.	648449-05-2
Molecular Formula	C9H5ClN2O
Molecular Weight	192.60 g/mol
Synonyms	6-Formyl-4-chloroquinazoline; 4-Chloro-6-quinazolinecarboxaldehyde; 4-Chloroquinazoline-6-carboxaldehyde; 4-Chloro-6-formylquinazoline; Quinazoline, 4-chloro-6-formyl-; 648449-05-2; 4-Chloro-6-quinazolinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloroquinazoline-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.