Description

2,5-Methano-2H-Furo[3,2-B]Pyrrol-6-Ol, Hexahydro-4-Methyl-, (2R,3As,5R,6R,6Ar)-Rel-(-)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, fused-ring structure which serves as a critical chiral building block in modern synthetic organic chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for potential new chemical entities (NCEs).
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and natural product analog creation.

Basic Information

Product Name	2,5-Methano-2H-Furo[3,2-B]Pyrrol-6-Ol, Hexahydro-4-Methyl-, (2R,3As,5R,6R,6Ar)-Rel-(-)- (9Ci)
CAS No.	646530-82-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	rel-(-)-Hexahydro-4-methyl-2,5-methano-2H-furo[3,2-b]pyrrol-6-ol; (2R,3aS,5R,6R,6aR)-Hexahydro-4-methyl-2,5-methano-2H-furo[3,2-b]pyrrol-6-ol; 2,5-Methano-2H-furo[3,2-b]pyrrol-6-ol, hexahydro-4-methyl-, (2R,3aS,5R,6R,6aR)-rel-(-)-; Fused furopyrrolidine alcohol derivative; Chiral furo[3,2-b]pyrrole intermediate.
EINECS	Contact for details

Quality Control

Our high-value chemical intermediates are produced under strict quality management systems. Each batch of 2,5-Methano-2H-Furo[3,2-B]Pyrrol-6-Ol, Hexahydro-4-Methyl-, (2R,3As,5R,6R,6Ar)-Rel-(-)- (9Ci) undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to preserve stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.