Description

3H-Fluorene-3,4,9-Triol, 4,9-Dihydro-, (3S,4R,9R)- (9Ci) is a high-purity, stereochemically defined organic compound with the CAS number 646507-14-4. This chiral fluorene derivative serves as a critical advanced intermediate for the synthesis of complex molecules in pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, asymmetric synthesis, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring a chiral, polyhydroxylated fluorene core structure.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Asymmetric Synthesis: Serves as a chiral starting material or ligand precursor in catalytic asymmetric reactions due to its defined (3S,4R,9R) stereochemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for creating compound libraries for high-throughput screening.

Basic Information

Product Name	3H-Fluorene-3,4,9-Triol, 4,9-Dihydro-, (3S,4R,9R)- (9Ci)
CAS No.	646507-14-4
Molecular Formula	C13H10O3
Molecular Weight	214.22 g/mol
Synonyms	(3S,4R,9R)-4,9-Dihydro-3H-fluorene-3,4,9-triol; (3S,4R,9R)-3,4,9-Trihydroxy-4,9-dihydro-3H-fluorene; 4,9-Dihydro-3H-fluorene-3,4,9-triol, (3S,4R,9R)-; 646507-14-4; (3S,4R,9R)-Dihydrofluorenetriol; Fluorene-3,4,9-triol derivative (chiral)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) are provided, detailing results for assay, enantiomeric excess, and impurity profiles. We adhere to a quality management system to ensure traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.