Description

3-Amino-3,4-Dihydro-4-Oxo-2-{[(Tetrahydrofur-2-Yl)Methyl]Carbamoyl}Quinazoline, 2-({[(3-Amino-3,4-Dihydro-4-Oxoquinazolin-2-Yl)Carbonyl]Amino}Methyl)Furan is a complex heterocyclic organic compound featuring a quinazolinone core linked to a tetrahydrofuran moiety via a carbamoyl bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Research: Potential application as a tool compound or inhibitor in biochemical assays and proteomics research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value heterocyclic compounds.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials or niche APIs.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and methodological studies.

Basic Information

Item	Details
Product Name	3-Amino-3,4-Dihydro-4-Oxo-2-{[(Tetrahydrofur-2-Yl)Methyl]Carbamoyl}Quinazoline, 2-({[(3-Amino-3,4-Dihydro-4-Oxoquinazolin-2-Yl)Carbonyl]Amino}Methyl)Furan
CAS No.	646497-34-9
Molecular Formula	C15H15N5O4
Molecular Weight	329.31 g/mol
Synonyms	2-({[(3-Amino-4-oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)furan; 3-Amino-2-[(tetrahydrofuran-2-ylmethyl)carbamoyl]-3,4-dihydroquinazolin-4-one; 2-[(3-Amino-4-oxo-3H-quinazolin-2-yl)formamido]methyltetrahydrofuran; 646497-34-9; Quinazoline-2-carboxamide, N-[(tetrahydro-2-furanyl)methyl]-3-amino-3,4-dihydro-4-oxo-; Tetrahydrofurfuryl 3-amino-4-oxo-3,4-dihydroquinazoline-2-carboxylate derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.