Description

5,6-Dichloroquinolin-8-Amine is a halogenated quinoline derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its significance lies in its bifunctional structure, featuring both a halogenated aromatic system and a primary amine group, enabling its use in the construction of complex heterocyclic scaffolds. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobial agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Precursor: Employed in the synthesis of organic ligands for metal-organic frameworks (MOFs) or as a monomer for specialty polymers with unique electronic or optical properties.
• Dye and Pigment Synthesis: Serves as an intermediate for creating advanced colorants and fluorescent markers due to the quinoline structure's chromophoric properties.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university laboratories and contract research organizations (CROs).

Basic Information

Product Name	5,6-Dichloroquinolin-8-Amine
CAS No.	644986-94-7
Molecular Formula	C9H6Cl2N2
Molecular Weight	213.06 g/mol
Synonyms	8-Amino-5,6-dichloroquinoline; 5,6-Dichloro-8-quinolinamine; 5,6-Dichloro-8-aminoquinoline; 8-Quinolinamine, 5,6-dichloro-; 5,6-Dichloroquinolin-8-ylamine; 5,6-Dichloro-8-quinolylamine
EINECS	Contact for details

Quality Control

Our 5,6-Dichloroquinolin-8-Amine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). As a fine chemical intermediate, prolonged exposure to moisture, heat, or direct light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.