Description

2-Fluoro-6-Trifluoromethyl-Benzylamine Hydrochloride is a high-purity, fluorinated benzylamine derivative supplied as a hydrochloride salt, offering enhanced stability and handling properties. This compound is a critical pharmaceutical intermediate and organic building block, valued for its unique trifluoromethyl and fluorine substituents which are instrumental in modulating the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, where the fluorine atoms enhance compound uptake and environmental stability.
• Ligand & Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probe Synthesis: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Fluoro-6-Trifluoromethyl-Benzylamine Hydrochloride
CAS No.	643088-07-7
Molecular Formula	C9H8ClF4N
Molecular Weight	241.61 g/mol
Synonyms	(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine hydrochloride; 1-(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine hydrochloride; α-Amino-2-fluoro-α,α,α-trifluoro-p-xylene hydrochloride; 2-Fluoro-α,α,α-trifluoro-p-toluidine hydrochloride; Benzenemethanamine, 2-fluoro-6-(trifluoromethyl)-, hydrochloride; 2-Fluoro-6-trifluoromethylbenzylamine HCl; 2-Fluoro-α,α,α-trifluoro-p-tolylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Trifluoromethyl-Benzylamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We adhere to relevant cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.